Multiplexed Processing of Vibrotactile Information in the Mouse Primary Somatosensory Cortex

Thalamocortical connections of the primary somatosensory cortex

  Although each subdivision of primary somatosensory cortex (SI) receives dense input from the thalamus, but the exact location and type of information that the fibers convey have not been identified yet. In the present study, the exact source of thalamocortical fibers to areas 2 and 3b was investigated using tract-tracing techniques. Following injection of tracer into area 3b, labeled neurons ...

Vision of the body modulates processing in primary somatosensory cortex.

Viewing the body affects somatosensory processing, even when entirely non-informative about stimulation. While several studies have reported effects of viewing the body on cortical processing of touch and pain, the neural locus of this modulation remains unclear. We investigated whether seeing the body modulates processing in primary somatosensory cortex (SI) by measuring short-latency somatose...

Properties of the primary somatosensory cortex projection to the primary motor cortex in the mouse.

The primary somatosensory (S1) and primary motor (M1) cortices are reciprocally connected, and their interaction has long been hypothesized to contribute to coordinated motor output. Very little is known, however, about the nature and synaptic properties of the S1 input to M1. Here we wanted to take advantage of a previously developed sensorimotor slice preparation that preserves much of the S1...

Role of mGluR5 and FMRP in Mouse Primary Somatosensory Cortex

Involvement of human primary somatosensory cortex in vibrotactile detection depends on task demand

UNLABELLED Detecting and discriminating sensory stimuli are fundamental functions of the nervous system. Electrophysiological and lesion studies suggest that macaque primary somatosensory cortex (SI) is critically involved in discriminating between stimuli, but is not required simply for detecting stimuli. By contrast, transcranial magnetic stimulation (TMS) studies in humans have shown near-co...